Yes, you can use all the ‘stuff’ that as a designer you deem appropriate to your audience and message, and still have a site that is accessible, and passes ‘Bobby’ (and other accessibility tools) accessibility checks.
However, what is required when using these technologies is a bit of clear thinking about what their purpose is on your site, and how, if the content is important, their functionality or message can be provided in alternative ways.
Admittedly it is not all easy, captioning of multimedia for instance is a specialist and difficult skill to master, but most accessibility techniques are not ‘rocket science’ and will actually add to the ‘richness’ of the experience for your visitors, rather than detract from it.
I provided feedback on the WCAG 2 (as representative of Guild of Accessible Website Designers) have two decades of experience and worked with hundreds of organisations.
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